Tissue Antigens. 2009 Oct;74(4):354-6.

In a study for acne vulgaris, sequence-based HLA typing showed a novel DPB1 allele, DPB1*2402.

Witter K, Kirchner E, Borelli C, Messer G, Albert T, Zahn R, Kauke T.

Source

Labor für Immungenetik, University Munich, Germany. klaus.witter@med.unimuenchen.de

Abstract

In this paper, we characterize the novel human leucocyte antigen (HLA)-DPB1*2402 allele that we found in a patient suffering from acne vulgaris. In comparison to the closest related allele DPB1*0401, HLA-DPB1*2402 has a single nucleotide exchange at position 115 (202), T replaces G. In consequence, codon 39 (68) TAC encodes for tyrosine in the novel allele instead of aspartic acid 39 (68) GAC in DPB1*0401.

PMID:: 19775376; [PubMed - indexed for MEDLINE]

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