Beta-amidoaldehydes via oxazoline hydroformylation

Chem Commun (Camb). 2009 Oct 14:(38):5704-6. doi: 10.1039/b913698c. Epub 2009 Sep 1.

Abstract

4-Substituted oxazolines, which are readily synthesized from naturally occurring alpha-amino acids, are converted efficiently and stereospecifically to beta-amidoaldehydes in the presence of synthesis gas and catalytic dicobalt octacarbonyl.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aldehydes / chemistry*
  • Catalysis
  • Cobalt / chemistry
  • Gases / chemistry
  • Molecular Conformation
  • Oxazoles / chemistry*
  • Stereoisomerism

Substances

  • Aldehydes
  • Gases
  • Oxazoles
  • Cobalt
  • dicobalt octacarbonyl