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Cell. 2009 Sep 18;138(6):1060-2. doi: 10.1016/j.cell.2009.09.004.

p53: a new kingpin in the stem cell arena.

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  • 1Department of Molecular Oncology, University of British Columbia, Vancouver, BC, Canada.


Identifying new regulators of the stem cell state offers potential for future gains in biomedicine. Evidence that the tumor suppressor p53 is a key regulator of the stem cell state (Cicalese et al., 2009) suggests a broad role for this protein and its pathways in the control of normal tissue homeostasis and tumor formation.

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