Hairy cell leukemia presenting as multiple discrete hepatic lesions

World J Gastroenterol. 2009 Sep 21;15(35):4453-6. doi: 10.3748/wjg.15.4453.

Abstract

The involvement of hairy cell leukemia in the liver is in the form of portal and sinusoidal cellular infiltration. Here we describe the first case of hepatic hairy cell leukemia presenting as multiple discrete lesions, which was treated successfully. We suggest that in the investigation of discrete hepatic lesions in cases of cancer of unknown primary, hairy cell leukemia should be considered. The excellent response of hairy cell leukemia to therapy highlights the need for such a consideration.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Cladribine / therapeutic use
  • Diagnosis, Differential
  • Humans
  • Leukemia, Hairy Cell / diagnosis*
  • Leukemia, Hairy Cell / drug therapy
  • Leukemia, Hairy Cell / pathology
  • Liver / pathology*
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / pathology
  • Male
  • Middle Aged
  • Organ Size
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Cladribine