Infectious Diseases Division, Washington University School of Medicine, USA. kwoeltje@dom.wustl.edu
Infections caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have become epidemic over the last decade. It causes a spectrum of diseases in humans but skin and soft tissue infections predominate. Molecular virulence factors in CA-MRSA are incompletely understood. In this article, the epidemiology, presentation, treatment, and surveillance of skin and soft tissue infections due to CA-MRSA are reviewed.