Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Trends Parasitol. 2009 Nov;25(11):517-24. doi: 10.1016/j.pt.2009.08.001. Epub 2009 Sep 9.

The heart of darkness: growth and form of Trypanosoma brucei in the tsetse fly.

Author information

  • 1Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK. reuben@vet.upm.edu.my

Abstract

The first description of African trypanosomes was made over a century ago. The importance of the tsetse in transmission and cyclic development of trypanosomes was discovered soon afterwards, and has been the focus of numerous studies since. However, investigation of trypanosomes in tsetse flies requires high resource investment and unusual patience; hence, many facets of trypanosome biology in the tsetse remain to be characterised despite the long history of research. Here, current knowledge and questions about some of the developmental changes in trypanosomes that occur in tsetse flies are summarised, along with recent technical advances that can now be used to provide some answers.

PMID:
19747880
[PubMed - indexed for MEDLINE]
PMCID:
PMC3770903
Free PMC Article

Images from this publication.See all images (3)Free text

Figure 1
Figure 2
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk