Display Settings:

Format

Send to:

Choose Destination
Can J Cardiol. 2009 Sep;25(9):e329-31.

Cesium chloride-induced torsades de pointes.

Author information

  • 1Department of Pharmacy, Chilliwack General Hospital, Chilliwack, British Columbia, Canada. mowiens@interchange.ubc.ca

Abstract

The chloride salt of cesium, a group 1A element, is gaining popularity as an alternative treatment of advanced cancers. Cesium chloride has primarily been used in cardiovascular research for arrhythmogenesis in animals because of its potassium-blocking effects. The present report describes a 45-year-old woman with metastatic breast cancer who experienced repeated episodes of torsades de pointes polymorphic ventricular tachycardia after several months of oral cesium therapy. There was a clear temporal relationship between cesium ingestion and the arrhythmia, which later resolved following discontinuation of cesium therapy. Serial cesium plasma and whole blood levels were measured over the ensuing six months and pharmacokinetic analysis was performed.

PMID:
19746253
[PubMed - indexed for MEDLINE]
PMCID:
PMC2780897
Free PMC Article

Images from this publication.See all images (4)Free text

Figure 1)
Figure 2)
Figure 3)
Figure 4)
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk