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Neurochirurgie. 2009 Oct;55(4-5):454-8. doi: 10.1016/j.neuchi.2009.07.001. Epub 2009 Sep 9.

[Pathologic characteristics of the most frequent peripheral nerve tumors].

[Article in French]

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  • 1Service d'anatomie et cytologie pathologiques, unité de pathologie ultrastructurale et expérimentale, CHU La Milétrie, 2, rue de la Milétrie, BP 577, 86021 Poitiers cedex, France.


Benign tumors of the peripheral nerves come from ectodermic tissues. This chapter describes the most common forms: the schwannomas and the neurofibromas. Schwannomas have two possible patterns of cells: Antoni A and B types. Neurofibromas are most often associated with neurofibromatosis NF1 and may be localized, diffuse, or plexiform. The benign tumor structures account for the fact that they can be removed with or without preserving the concerned nerve. Malignant tumors (malignant peripheral sheath tumors) come from degeneration of neurofibromas in two out of three cases and have a poor prognosis.

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