Calcifying epithelial odontogenic tumour (CEOT), also known as Pindborg tumour, is a rare, benign odontogenic neoplasm. A case of an intra-osseous CEOT in the maxilla is presented in which unilateral nasal obstruction and progressive difficulty in breathing were the first clinical symptoms. Dental practitioners might be the first clinicians to come across such tumours, during investigation of missing or non-erupted maxillary teeth, ie canines, and they should be alerted by any unilateral nasal obstruction symptoms. Diagnostic features and treatment options of the tumour are discussed in relation to its histological typing. CLINICAL RELEVANCE: This manuscript highlights the importance of accurate clinical and radiographic investigation for the dental practitioner when assessing missing maxillary teeth.