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    Results: 7

    1.

    Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation.

    Yonashiro R, Sugiura A, Miyachi M, Fukuda T, Matsushita N, Inatome R, Ogata Y, Suzuki T, Dohmae N, Yanagi S.

    Mol Biol Cell. 2009 Nov;20(21):4524-30. Epub 2009 Sep 9.

    PMID:
    19741096
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.

    Ying Z, Wang H, Fan H, Zhu X, Zhou J, Fei E, Wang G.

    Hum Mol Genet. 2009 Nov 15;18(22):4268-81. Epub 2009 Aug 6.

    PMID:
    19661182
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.

    Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G.

    J Biol Chem. 2007 Sep 21;282(38):28087-95. Epub 2007 Jul 31.

    PMID:
    17666395
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity.

    Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G.

    Neurobiol Dis. 2007 Feb;25(2):331-41. Epub 2006 Dec 6.

    PMID:
    17157513
    [PubMed - indexed for MEDLINE]
    5.

    Physical and functional interaction between Dorfin and Valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders.

    Ishigaki S, Hishikawa N, Niwa J, Iemura S, Natsume T, Hori S, Kakizuka A, Tanaka K, Sobue G.

    J Biol Chem. 2004 Dec 3;279(49):51376-85. Epub 2004 Sep 29.

    PMID:
    15456787
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    Co-chaperone CHIP associates with mutant Cu/Zn-superoxide dismutase proteins linked to familial amyotrophic lateral sclerosis and promotes their degradation by proteasomes.

    Choi JS, Cho S, Park SG, Park BC, Lee DH.

    Biochem Biophys Res Commun. 2004 Aug 27;321(3):574-83.

    PMID:
    15358145
    [PubMed - indexed for MEDLINE]
    7.

    Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity.

    Niwa J, Ishigaki S, Hishikawa N, Yamamoto M, Doyu M, Murata S, Tanaka K, Taniguchi N, Sobue G.

    J Biol Chem. 2002 Sep 27;277(39):36793-8. Epub 2002 Jul 26.

    PMID:
    12145308
    [PubMed - indexed for MEDLINE]
    Free Article

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