Send to:

Choose Destination
See comment in PubMed Commons below
Microbes Infect. 2009 Dec;11(14-15):1197-205. doi: 10.1016/j.micinf.2009.09.002. Epub 2009 Sep 6.

Focus on Chikungunya pathophysiology in human and animal models.

Author information

  • 1Groupe Microorganismes et Barrières de l'Hôte, Institut Pasteur, Paris, France.


Chikungunya virus (CHIKV) is an arbovirus responsible for acute febrile arthralgia. It re-emerged abruptly in 2005 and caused a massive outbreak in the Indian Ocean region, and then extended to Asia. Here we review the pathophysiology of CHIKV infection, based on human and mouse studies, and also present prospects for prevention and therapy of this infection. Our results are discussed in the light of the current knowledge regarding other arthritogenic Alphaviruses.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk