Cell. 2009 Sep 4;138(5):834-6.

IKKepsilon: a bridge between obesity and inflammation.

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Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA. jolefsky@ucsd.edu

Abstract

Obesity leads to tissue inflammation and insulin resistance, which are features of metabolic diseases such as type 2 diabetes. Chiang et al. (2009) now show that the IkappaB kinase IKKepsilon is an important link between obesity and inflammation and may be a new therapeutic target for treating obesity-related metabolic diseases.

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Cell. 2009 Sep 4;138(5):961-75.

PMID:: 19737512; [PubMed - indexed for MEDLINE]

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I-kappa B Kinase

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