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Vaccine. 2009 Nov 5;27(47):6546-9. doi: 10.1016/j.vaccine.2009.08.050. Epub 2009 Sep 1.

Evaluation of self-reported and registry-based influenza vaccination status in a Wisconsin cohort.

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  • 1Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI 54449, USA.


We evaluated influenza vaccination status as determined by self-report and a regional, real-time immunization registry during two influenza seasons when subjects were enrolled in a study to estimate vaccine effectiveness. We enrolled 2907 patients during the two consecutive seasons. The sensitivity and specificity of self-reported influenza vaccination when compared to immunization registry records were 95% and 90%, respectively. The positive predictive value of self-reported vaccination was 89% and negative predictive value was 96%. In our study population, self-reported influenza vaccine status was a sensitive and fairly specific indicator of actual vaccine status. Misclassification was more common among young children.

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