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Radiother Oncol. 2009 Nov;93(2):298-301. doi: 10.1016/j.radonc.2009.07.006. Epub 2009 Aug 28.

A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy.

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  • 1Department of Radiation and Cellular Oncology, University of Chicago, IL, USA.

Abstract

Using previous dosimetric analysis methods, we identified the volume of bowel receiving 30 Gy (V(30)) correlated with acute gastrointestinal (GI) toxicity in anal cancer patients treated with intensity-modulated radiation therapy and concurrent chemotherapy. For V(30)>450 cc and < or =450 cc, acute GI toxicity was 33% and 8%, respectively (p=0.003).

PMID:
19717198
[PubMed - indexed for MEDLINE]
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