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J Plast Reconstr Aesthet Surg. 2010 Sep;63(9):1443-6. doi: 10.1016/j.bjps.2009.07.045. Epub 2009 Aug 27.

Botulinum toxin injection pain relief using a topical anesthetic skin refrigerant.

Author information

  • 1Department of Plastic Surgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

Abstract

BACKGROUND:

This study was performed to determine if pretreatment application of a topical anesthetic skin refrigerant reduced discomfort during botulinum toxin injection.

METHODS:

Twenty patients were assigned to four groups determined by side of the face pretreated with skin refrigerant and side receiving the first injection. On a Visual Analog Scale of 0-10 patients rated discomfort levels after injections in the glabellar complex with and without pretreatment.

RESULTS:

Mean discomfort rating for the pretreated side was 3.1, while the mean discomfort rating for the non-pretreated side was 4.5. Discomfort was not affected by the side sprayed (p=0.33) nor by administering the injection to the sprayed side first (p=0.37). The paired t-test revealed a significant difference between discomfort levels on the pretreated and non-pretreated sides (p=0.038) yielding a 95% confidence interval of (-2.71, -0.09).

CONCLUSIONS:

Topical anesthetic skin refrigerant significantly reduces discomfort in a cost-effective manner for reported by patients undergoing botulinum injections.

Copyright 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

PMID:
19716355
[PubMed - indexed for MEDLINE]
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