Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles

Chem Commun (Camb). 2009 Sep 21:(35):5236-8. doi: 10.1039/b912093a. Epub 2009 Aug 6.

Abstract

Highly useful halogenated benzofurans and benzothiophenes are prepared from readily available gem-dibromoolefins using a mild, ligand-free copper catalyzed cross-coupling procedure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry*
  • Benzofurans / chemical synthesis*
  • Benzofurans / chemistry
  • Catalysis
  • Copper / chemistry
  • Halogenation
  • Thiophenes / chemical synthesis*
  • Thiophenes / chemistry

Substances

  • Alkenes
  • Benzofurans
  • Thiophenes
  • benzothiophene
  • Copper