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J Vasc Surg. 2009 Dec;50(6):1477-80. doi: 10.1016/j.jvs.2009.06.015. Epub 2009 Aug 22.

Aortic angiosarcoma masquerading as a thoracic aortic aneurysm.

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  • 1Division of Vascular Surgery, Department of Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA.


Aortic angiosarcoma is an exceedingly rare clinical entity. Significant delay in diagnosis can occur due to a low index of suspicion on the part of the clinician. We report a case of aortic angiosarcoma masquerading as a descending thoracic aneurysm arising from a penetrating ulcer. The patient was initially treated with an endovascular stent graft for rapid growth, but the lesion continued to enlarge despite angiographic exclusion. FDG-PET CT scan and biopsy ultimately confirmed the diagnosis of aortic angiosarcoma. This case highlights some of the difficulties of making the early diagnosis of aortic angiosarcoma.

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