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This review will summarize a limited number of experimental studies concerning effects of tranquilizers, muscle relaxants, and antihistamine drugs, as well as combinations of these drugs with ethanol, on human performance related to driving. The first group of studies utilized batteries of psychological and/or psychomotor tests to assess drug effects, while the second group used driving simulators. Procedures and results of each study will be summarized, and this will be followed by a general critique of methodologies which have been used along with suggestions for improved methodologies.
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