Source
Department of Dermatology, University of Rome La Sapienza, Rome, Italy. ilcapo75@gmx.net
Abstract
BACKGROUND:
Linear immunoglobulin A bullous dermatosis (LABD) is an autoimmune subepidermal blistering disease, rarely induced by drugs.
METHODS:
We describe a case of a 47-year-old man who developed a severe blistering eruption after therapy with amoxicillin-clavulanic acid.
RESULTS:
Histopathologic examination and direct immunofluorescence were consistent with a diagnosis of LABD. Therapy with dapsone controlled the disease but, after sun exposure, there was a worsening of the illness.
CONCLUSION:
To our knowledge, this is the first case of amoxicillin-clavulanic acid-induced LABD in an adult.