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    Nat Genet. 2009 Sep;41(9):965-7. Epub 2009 Aug 23.

    Genomic privacy and limits of individual detection in a pool.

    Sankararaman S, Obozinski G, Jordan MI, Halperin E.

    Computer Science Division, University of California, Berkeley, Berkeley, California, USA.

    Recent studies have demonstrated that statistical methods can be used to detect the presence of a single individual within a study group based on summary data reported from genome-wide association studies (GWAS). We present an analytical and empirical study of the statistical power of such methods. We thereby aim to provide quantitative guidelines for researchers wishing to make a limited number of SNPs available publicly without compromising subjects' privacy.

    PMID: 19701190 [PubMed - indexed for MEDLINE]

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