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J Dtsch Dermatol Ges. 2009 Dec;7(12):1065-7. doi: 10.1111/j.1610-0387.2009.07209.x.

Cutaneous gamma/delta T-cell lymphoma.

[Article in English, German]

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  • 1Eduard-Arning Clinic for Dermatology and Allergology Asklepios Klinik St. Georg, Lohm├╝hlenstra├če 5, Hamburg, Germany.


Only 40 cases of primary cutaneous gamma/delta T-cell lymphoma (GD-TCL) have been described. GD-TCL was included as a provisional entity in the WHO-EORTC classification of cutaneous lymphomas in 2005. GD-TCL often failed to respond to polychemotherapy and radiation therapy and have a poor prognosis with a mean survival of only 15 months. We present a patient treated with surgery, immunomodulatory therapy, and polychemotherapy. He then received hematopoietic stem cell transplantation and has been in complete remission since. Allogeneic stem cell transplantation appears to be a promising therapeutic option for aggressive and generally fatal lymphomas like GD-TCL.

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