My NCBISign In

Display Settings:

Format

Send to:

Choose Destination
    J Hepatol. 2009 Nov;51(5):967-9. Epub 2009 Jul 10.

    Acute hepatitis due to brivudin: a case report.

    Mottu A, Rubbia-Brandt L, Bihl F, Hadengue A, Spahr L.

    Source

    General Internal Medicine, University Hospitals, Geneva, Switzerland.

    Abstract

    BACKGROUND/AIMS:

    Brivudin is licensed in several European countries for the treatment of herpetic infections, and is considered safe (approximately 1% of patients with transient elevation of liver enzymes) in large multicenter trials.

    METHODS:

    We report a case of acute brivudin hepatitis documented with a liver biopsy in detail.

    RESULTS:

    Liver biopsy demonstrated acute liver injury with a predominant cytolytic pattern and features suggestive of a drug-induced immunoallergic hepatitis. Elevated ALT levels returned to normal within weeks.

    CONCLUSIONS:

    This is the first published case of acute immunoallergic hepatitis due to brivudin.

    PMID:
    19692139
    [PubMed - indexed for MEDLINE]

    Publication Types, MeSH Terms, Substances

    Publication Types

    MeSH Terms

    Substances

    LinkOut - more resources

    Full Text Sources

    Other Literature Sources

    Molecular Biology Databases

      Supplemental Content

      Icon for Elsevier Science

      Save items

      loading

      Related citations in PubMed

      See reviews... See all...

      Related information

      • Related Citations
        Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
      • Compound (MeSH Keyword)
        PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
      • Substance (MeSH Keyword)
        PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      You are here: NCBI > Literature > PubMed
      Write to the Help Desk