From the *Quebec National Public Health Institute, Quebec, Canada; daggerLaval University Research Hospital Center, Quebec, Canada; and double daggerQuebec Public Health Laboratory, Quebec, Canada.
A total of 465 children aged 8 to 10 years were vaccinated with 2 doses of Recombivax-HB 2.5 mug (RB) or Twinrix-Junior 10 mug/360 EL.U (TX), according to a 0 and 6 months schedule. Seven years postsecond dose, a challenge dose of vaccine was given. All vaccinees in the TX and 98% in the RB group showed an anamnestic response. Vaccination at the age of 8 to 10 years with two-pediatric doses of TX or RB given with a 6 months interval induces a long-lasting immunity in most vaccinees.