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Ital J Gastroenterol. 1990 Dec;22(6):350-1.

High prevalence of co-occurrence of anti-HCV and anti-HBc antibodies in chronic hepatitis patients from southern Italy.

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  • 1Clinical Malattie Infettive, 1. Facolt√† di Medicina, Universit√† di Napoli, Italy.


The prevalence of anti-HCV and anti-HBV antibodies was investigated in a series of 77 adult patients with HBsAg negative, non autoimmune chronic liver disease. Anti-HCV were found in 68% and anti-HBc in 71% of the cases; 68% of the patients carried both antibodies. There was no difference in the proportion of anti-HBc positive cases between the anti-HCV positive or negative patients. The intense circulation of HBV infection in Southern Italy during the past decades might explain the high percentage of subjects with anti-HBc. Whether the co-occurrence of HCV and HBV infection may influence the natural history of the liver disease, remains to be established.

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