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Bioinformatics. 2009 Oct 1;25(19):2617-8. doi: 10.1093/bioinformatics/btp464. Epub 2009 Aug 3.

Genoscape: a Cytoscape plug-in to automate the retrieval and integration of gene expression data and molecular networks.

Author information

  • 1Biotechnology Center, TU Dresden, Dresden, Germany. Mathieu.clement-ziza@biotec.tu-dresden.de

Abstract

Genoscape is an open-source Cytoscape plug-in that visually integrates gene expression data sets from GenoScript, a transcriptomic database, and KEGG pathways into Cytoscape networks. The generated visualisation highlights gene expression changes and their statistical significance. The plug-in also allows one to browse GenoScript or import transcriptomic data from other sources through tab-separated text files. Genoscape has been successfully used by researchers to investigate the results of gene expression profiling experiments.

AVAILABILITY:

Genoscape is an open-source software freely available from the Genoscape webpage (http://www.pasteur.fr/recherche/unites/Gim/genoscape/). Installation instructions and tutorial can also be found at this URL.

PMID:
19654116
[PubMed - indexed for MEDLINE]
PMCID:
PMC2752617
Free PMC Article

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