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Biomark Insights. 2009 Feb 9;4:27-32.

Breath hydrogen produced by ingestion of commercial hydrogen water and milk.

Author information

  • 1Department of Etiology and Pathogenesis, National Cardiovascular Center Research Institute, Japan.

Abstract

OBJECTIVE:

To compare how and to what extent ingestion of hydrogen water and milk increase breath hydrogen in adults.

METHODS:

Five subjects without specific diseases, ingested distilled or hydrogen water and milk as a reference material that could increase breath hydrogen. Their end-alveolar breath hydrogen was measured.

RESULTS:

Ingestion of hydrogen water rapidly increased breath hydrogen to the maximal level of approximately 40 ppm 10-15 min after ingestion and thereafter rapidly decreased to the baseline level, whereas ingestion of the same amount of distilled water did not change breath hydrogen (p < 0.001). Ingestion of hydrogen water increased both hydrogen peaks and the area under the curve (AUC) of breath hydrogen in a dose-dependent manner. Ingestion of milk showed a delayed and sustained increase of breath hydrogen in subjects with milk intolerance for up to 540 min. Ingestion of hydrogen water produced breath hydrogen at AUC levels of 2 to 9 ppm hour, whereas milk increased breath hydrogen to AUC levels of 164 ppm hour for 540 min after drinking.

CONCLUSION:

Hydrogen water caused a rapid increase in breath hydrogen in a dose-dependent manner; however, the rise in breath hydrogen was not sustained compared with milk.

KEYWORDS:

breath hydrogen; colonic fermentation; hydrogen water; milk

PMID:
19652760
[PubMed]
PMCID:
PMC2716677
Free PMC Article
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