Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Biol. 2009 Jul 28;19(14):R558-61. doi: 10.1016/j.cub.2009.06.017.

Limb development: the rise and fall of retinoic acid.

Author information

  • 1Cancer and Developmental Biology Laboratory, National Cancer Institute, NCI-Frederick, Frederick, MD 21702, USA. mlewandoski@mail.ncifcrf.gov

Abstract

Retinoic acid was thought to play a key instructive role during limb bud initiation and subsequent patterning. New results argue instead that its role is permissive: retinoic acid is essential only to antagonize early axial Fgf signals that otherwise inhibit the limb field.

PMID:
19640492
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk