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Vascular Biology Program, Departments of Surgery and Pathology, Harvard Medical School, Boston, MA 02115, USA. andrew.dudley@childrens.harvard.edu
The field of antiangiogenesis research has been met with some surprises, including the realization that tumor blood vessels are more complex and labile than expected. In this issue of Clinical Cancer Research, Xiong and colleagues show that tumor-specific endothelial cells are less sensitive to cytotoxic and antiangiogenic drugs compared to their normal counterparts.
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