Skin Res Technol. 2009 Aug;15(3):253-61.

Use of various models for in vitro percutaneous absorption studies of ultraviolet filters.

Huong SP, Bun H, Fourneron JD, Reynier JP, Andrieu V.

Source

Laboratoire de Pharmacie Galénique Industrielle et Cosmétologie, Université de la Méditerranée, Marseille, Cedex 05, France.

Abstract

BACKGROUND: The percutaneous absorption test aims to estimate the passage of a substance across the skin. The absorption process can be described in three steps: (a) penetration of a substance into the skin layer, followed by (b) penetration from one layer into another (permeation) and finally (c) resorption into the vascular system. In vivo and in vitro models are available but owing to ethical reasons as well as the latter providing greater feasibility, in vitro models are preferred. AIMS: This present study reviews the natural membranes (human skin and animal models: pig, rabbit, rat, hairless mouse, guinea-pig and mouse), artificial skin equivalents and synthetic membranes that are currently being used for in vitro percutaneous absorption studies of UV filters, in order to provide the researcher with a greater insight when selecting membrane models for given experimental conditions.

PMID:: 19630207; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Sunscreening Agents

LinkOut - more resources

Full Text Sources

Medical

Sun Exposure - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

In vitro evaluation of concurrent use of commercially available insect repellent and sunscreen preparations. [Br J Dermatol. 2005]
In vitro evaluation of concurrent use of commercially available insect repellent and sunscreen preparations.
Gu X, Wang T, Collins DM, Kasichayanula S, Burczynski FJ. Br J Dermatol. 2005 Jun; 152(6):1263-7.
Transdermal penetration of UV filters. [Skin Pharmacol Physiol. 2008]
Transdermal penetration of UV filters.
Klinubol P, Asawanonda P, Wanichwecharungruang SP. Skin Pharmacol Physiol. 2008; 21(1):23-9. Epub 2007 Oct 2.
Skin permeation and distribution of two sunscreens: a comparison between reconstituted human skin and hairless rat skin. [Skin Pharmacol Physiol. 2008]
Skin permeation and distribution of two sunscreens: a comparison between reconstituted human skin and hairless rat skin.
Monti D, Brini I, Tampucci S, Chetoni P, Burgalassi S, Paganuzzi D, Ghirardini A. Skin Pharmacol Physiol. 2008; 21(6):318-25. Epub 2008 Sep 11.
Review [Methods and models for percutaneous absorption studies of organophosphates]. [Pathol Biol (Paris). 2008]
Review [Methods and models for percutaneous absorption studies of organophosphates].
Boudry I, Trescos Y, Vallet V, Cruz C, Lallement G. Pathol Biol (Paris). 2008 Jul; 56(5):292-9. Epub 2008 Jan 11.
Review Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models. [Adv Drug Deliv Rev. 2007]
Review Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models.
Godin B, Touitou E. Adv Drug Deliv Rev. 2007 Sep 30; 59(11):1152-61. Epub 2007 Aug 16.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

Use of various models for in vitro percutaneous absorption studies of ultraviole...
Use of various models for in vitro percutaneous absorption studies of ultraviolet filters.
Skin Res Technol. 2009 Aug ;15(3):253-61.

PubMed
Strategic Advisory Group of Experts on Immunization - report of the extraordinar...
Strategic Advisory Group of Experts on Immunization - report of the extraordinary meeting on the influenza A (H1N1) 2009 pandemic, 7 July 2009.
Wkly Epidemiol Rec. 2009 Jul 24 ;84(30):301-4.

PubMed
Pharmacokinetics of low molecular weight heparins.
Pharmacokinetics of low molecular weight heparins.
Acta Chir Scand Suppl. 1990 ;556:57-61.

PubMed
Proceedings of the 4th World Symposium on Pulmonary Hypertension, February 2008,...
Proceedings of the 4th World Symposium on Pulmonary Hypertension, February 2008, Dana Point, California, USA.
J Am Coll Cardiol. 2009 Jun 30 ;54(1 Suppl):S1-117.

PubMed
Clinical application of subjective global assessment in Chinese patients with ga...
Clinical application of subjective global assessment in Chinese patients with gastrointestinal cancer.
World J Gastroenterol. 2009 Jul 28 ;15(28):3542-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: