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Clin Infect Dis. 2009 Sep 1;49(5):750-6. doi: 10.1086/605087.

The effect of universal influenza immunization on antibiotic prescriptions: an ecological study.

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  • 1Institute for Clinical Evaluative Sciences, University of Toronto, Canada.


The Canadian province of Ontario introduced universal influenza immunization in 2000, offering free vaccines to the entire population. We compared changes in rates of influenza-associated respiratory antibiotic prescriptions before and after universal immunization in Ontario with corresponding changes in other provinces. Universal influenza immunization is associated with reduced influenza-associated antibiotic prescriptions.

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