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    J Virol. 1977 Jul;23(1):106-9.

    Genetic studies of the Fv-1 locus of mice: linkage with Gpd-1 in recombinant inbred lines.

    Taylor BA, Bedigian HG, Meier H.

    Abstract

    Multiple recombinant inbred lines, derived from crosses between strains permissive to N-tropic murine leukemia viruses (Fv-1n) and strains permissive to B-tropic murine leukemia viruses (Fv-1b), have been characterized as to Fv-1 genotype and other chromosome 4 markers, including the closely linked hexose-6-phosphate dehydrogenase isozyme locus (Gpd-1). Only one recombinant between Fv-1 and Gpd-1 was found among 45 lines tested. On this basis, the distance between Fv-1 and Gpd-1 is estimated to be 0.6 centimorgans. None of the lines was either resistant or susceptible to both N- and B-tropic viruses. Nineteen other inbred strains, previously untested, were characterized as either Fv-1n or Fv-1b.

    PMID:
    196096
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC515805
    Free PMC Article

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