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J Acoust Soc Am. 2009 Jul;126(1):EL34-40. doi: 10.1121/1.3152266.

Natural frequency of a gas bubble in a tube: experimental and simulation results.

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  • 1Mechanical Engineering, University of Rochester, Rochester, New York 14627, USA.


Use of ultrasonically excited microbubbles within blood vessels has been proposed for a variety of clinical applications. In this paper, an axisymmetric coupled boundary element and finite element code and experiments have been used to investigate the effects of a surrounding tube on a bubble's response to acoustic excitation. A balloon model allowed measurement of spherical gas bubble response. Resonance frequencies match one-dimensional cylindrical model predictions for a bubble well within a rigid tube but deviate for a bubble near the tube end. Simulations also predict bubble translation along the tube axis and aspherical oscillations at higher amplitudes.

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