J Basic Clin Physiol Pharmacol. 2009;20(1):73-9.

Wound healing activity of flower extract of Calendula officinalis.

Source

Department of Biochemistry, Amala Cancer Research Centre Amala Nagar, Thrissur-680555, Kerala, India.

Abstract

The effects of oral and topical application of Calendula officinalis flower extract on excision wounds made in rats were checked. The parameters assessed were the days needed for re-epithelization and percentage of wound closure. The hydroxy proline and hexosamine content in the granuloma tissue of the wound was also measured. The percentage of wound closure was 90.0% in the extract-treated group, whereas the control group showed only 51.1% on the eighth day of wounding (p < .01). The days needed for re-epithelization were 17.7 for the control animals; extract treatment at a dose of 20 or 100 mg/kg b.wt reduced the period to 14 and 13 days, respectively. A significant increase was observed in the hydroxy proline and hexosamine content in the extract-treated group compared with the untreated animals. The data indicate potent wound healing activity ofC. officinalis extract.

PMID:: 19601397; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

Supplemental Content

Related citations

Catharanthus roseus flower extract has wound-healing activity in Sprague Dawley rats. [BMC Complement Altern Med. 2006]
Catharanthus roseus flower extract has wound-healing activity in Sprague Dawley rats.
Nayak BS, Pinto Pereira LM. BMC Complement Altern Med. 2006 Dec 21; 6:41. Epub 2006 Dec 21.
Evaluation of wound healing activity of Allamanda cathartica. L. and Laurus nobilis. L. extracts on rats. [BMC Complement Altern Med. 2006]
Evaluation of wound healing activity of Allamanda cathartica. L. and Laurus nobilis. L. extracts on rats.
Nayak S, Nalabothu P, Sandiford S, Bhogadi V, Adogwa A. BMC Complement Altern Med. 2006 Apr 5; 6:12. Epub 2006 Apr 5.
A preclinical study of the effects of seabuckthorn (Hippophae rhamnoides L.) leaf extract on cutaneous wound healing in albino rats. [Int J Low Extrem Wounds. 2005]
A preclinical study of the effects of seabuckthorn (Hippophae rhamnoides L.) leaf extract on cutaneous wound healing in albino rats.
Gupta A, Kumar R, Pal K, Banerjee PK, Sawhney RC. Int J Low Extrem Wounds. 2005 Jun; 4(2):88-92.
Review Final report on the safety assessment of Calendula officinalis extract and Calendula officinalis. [Int J Toxicol. 2001]
Review Final report on the safety assessment of Calendula officinalis extract and Calendula officinalis.
. Int J Toxicol. 2001; 20 Suppl 2:13-20.
Review Marigold (Calendula officinalis L.): an evidence-based systematic review by the Natural Standard Research Collaboration. [J Herb Pharmacother. 2006]
Review Marigold (Calendula officinalis L.): an evidence-based systematic review by the Natural Standard Research Collaboration.
Basch E, Bent S, Foppa I, Haskmi S, Kroll D, Mele M, Szapary P, Ulbricht C, Vora M, Yong S, et al. J Herb Pharmacother. 2006; 6(3-4):135-59.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Wound healing activity of flower extract of Calendula officinalis.
Wound healing activity of flower extract of Calendula officinalis.
J Basic Clin Physiol Pharmacol. 2009 ;20(1):73-9.

PubMed
Is higher dairy consumption associated with lower body weight and fewer metaboli...
Is higher dairy consumption associated with lower body weight and fewer metabolic disturbances? The Hoorn Study.
Am J Clin Nutr. 2007 Apr ;85(4):989-95.

PubMed
alpha-Glycerylphosphorylcholine administration increases the GH responses to GHR...
alpha-Glycerylphosphorylcholine administration increases the GH responses to GHRH of young and elderly subjects.
Horm Metab Res. 1992 Mar ;24(3):119-21.

PubMed
Five strategies for accelerating the war on cancer in an era of budget deficits.
Five strategies for accelerating the war on cancer in an era of budget deficits.
Oncologist. 2009 Feb ;14(2):110-6. Epub 2009 Jan 15 .

PubMed
Varicella infection and pneumonia among adults.
Varicella infection and pneumonia among adults.
Int J Infect Dis. 1998 Apr-Jun ;2(4):205-10.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Wound healing activity of flower extract of Calendula officinalis.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Supplemental Content

Related citations

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information