Differences in hip bone mineral density may explain the hip fracture pattern in osteoarthritic hips

Acta Orthop. 2009 Jun;80(3):308-13. doi: 10.3109/17453670903039528.

Abstract

Introduction: In patients with osteoarthritis of the hip (OAH), trochanteric fractures are much more common than femoral neck fractures. One reason may be altered bone composition in the proximal femurs. OAH often leads to a fixed external rotation of the hip, leading to difficulties in positioning during DXA measurements. We compared BMD in OAH-affected legs and healthy legs.

Patients and methods: 40 patients with strictly unilateral OAH were cross-sectionally investigated with DXA at the hips and heels bilaterally as well as body composition of the legs. 3 regions of interest in the proximal femur were measured: femoral neck (FN), trochanter (TR), and total hip (TH). The design of the study allowed us to perform paired t-test between the OAH side and the healthy side.

Results: BMD was increased by 4.1% in FN, and reduced by 8.3% in TR and 4.1% in TH (p < 0.001 for all comparisons).

Interpretation: The differences in BMD, with decrease in the trochanter and increase in the femoral neck, may offer an explanation for the pattern of hip fractures seen in osteoarthritis. External rotation of the hip cannot explain the differences in BMD.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon
  • Aged
  • Bone Density*
  • Cross-Sectional Studies
  • Female
  • Femoral Neck Fractures / etiology
  • Femoral Neck Fractures / metabolism
  • Femoral Neck Fractures / physiopathology*
  • Femur Neck / metabolism
  • Femur Neck / physiopathology*
  • Hip Fractures / etiology
  • Hip Fractures / metabolism
  • Hip Fractures / physiopathology*
  • Hip Joint / metabolism
  • Hip Joint / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Osteoarthritis, Hip / complications
  • Osteoarthritis, Hip / metabolism
  • Osteoarthritis, Hip / physiopathology*
  • Rotation
  • Weight-Bearing