South Med J. 2009 Aug;102(8):858-60.

Recovery time in a case of gemfibrozil and simvastatin-associated rhabdomyolysis.

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Department of Pharmacy Practice, Family and Community Medicine, Area Health Education Center-Northeast, University of Arkansas for Medical Sciences, Jonesboro, AR, USA. dcummins@ahecne.uams.edu

Abstract

Simvastatin is a cholesterol-lowering medication heavily prescribed to treat and prevent vascular disease. Despite widespread use, cases of simvastatin-induced rhabdomyolysis are rare. Little information is available regarding the recovery period for a patient who has experienced drug-induced rhabdomyolysis. We present a case involving a patient with multiple risk factors (advanced age, high-dose simvastatin therapy, concomitant nonsteroidal anti-inflammatory medication, and concomitant gemfibrozil therapy) and highlight his recovery course.

PMID:: 19593291; [PubMed - indexed for MEDLINE]

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Possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil. [J Intern Med. 1996]
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