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South Med J. 2009 Aug;102(8):858-60. doi: 10.1097/SMJ.0b013e3181ad6078.

Recovery time in a case of gemfibrozil and simvastatin-associated rhabdomyolysis.

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  • 1Department of Pharmacy Practice, Family and Community Medicine, Area Health Education Center-Northeast, University of Arkansas for Medical Sciences, Jonesboro, AR, USA.


Simvastatin is a cholesterol-lowering medication heavily prescribed to treat and prevent vascular disease. Despite widespread use, cases of simvastatin-induced rhabdomyolysis are rare. Little information is available regarding the recovery period for a patient who has experienced drug-induced rhabdomyolysis. We present a case involving a patient with multiple risk factors (advanced age, high-dose simvastatin therapy, concomitant nonsteroidal anti-inflammatory medication, and concomitant gemfibrozil therapy) and highlight his recovery course.

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