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Invest Radiol. 1977 Jul-Aug;12(4):368-72.

Evaluation of perfluoroctylbromide for lymphography in the dog: comparison with ethiodol.


The efficacy and safety of perfluoroctylbromide as a diagnostic contrast agent for direct lymphography was studied in mongrel dogs. This radiopaque perfluorocarbon has several advantages over Ethiodol. The liquid compound has injection times one-fifth of that required for Ethiodol. When dosages were three to four times that necessary for radiograms, the lungs of perfluoroctylbromide dogs tolerated the increase better than the Ethiodol dogs. Although the radiopacity is less, radiographs were acceptable. The less radiopacity of the fluoroctylbromide nodes may be of greater significance in the larger body of the human.

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