Central mineralocorticoid receptors and cardiovascular disease

Neuroendocrinology. 2009;90(3):245-50. doi: 10.1159/000227807. Epub 2009 Jul 7.

Abstract

The mineralocorticoid receptor (MR) is expressed in many cell types throughout the body, including specific neurons, and mediates diverse functions, many of which are just now being appreciated. MR that pertain to the central modulation of cardiovascular function and health are addressed herein.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aldosterone / metabolism
  • Animals
  • Blood Vessels / immunology
  • Blood Vessels / metabolism
  • Blood Vessels / pathology
  • Brain / physiology
  • Cardiovascular Diseases / metabolism*
  • Hemodynamics / physiology
  • Humans
  • Inflammation / metabolism
  • Kidney / immunology
  • Kidney / metabolism
  • Kidney / pathology
  • Myocardium / immunology
  • Myocardium / metabolism
  • Myocardium / pathology
  • Neurons / physiology
  • Receptors, Mineralocorticoid / metabolism*

Substances

  • Receptors, Mineralocorticoid
  • Aldosterone