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Clinics (Sao Paulo). 2009;64(6):535-41.

Surgical resection of lung metastases: results from 529 patients.

Author information

  • 1Department of Thoracic Surgery, Hospital do Cancer AC Camargo, São Paulo, Brazil. rnyounes@yahoo.com

Abstract

OBJECTIVE:

The aim of this study is to determine clinical, pathological, and treatment-relevant variables associated with long-term (90-month) overall survival in patients with lung metastases undergoing pulmonary metastasectomy.

METHODS:

A retrospective review was performed of patients who were admitted with lung metastases, and who underwent thoracotomy for resection, after treatment of a primary tumor. Data were collected regarding demographics, tumor features, treatment, and outcome.

RESULTS:

Patients (n = 529) were submitted to a total of 776 thoracotomies. Median follow-up time across all patients was 21.6 months (range: 0-192 months). The postoperative complication rate was 9.3%, and the 30-day mortality rate was 0.2%. The ninety-month overall survival rate for all patients was 30.4%. Multivariate analysis identified the number of pulmonary nodules detected on preoperative CT-scan, the number of malignant nodules resected, and complete resection as the independent prognostic factors for overall survival.

CONCLUSION:

These results confirm that lung metastasectomy is a safe and potentially curative procedure for patients with treated primary tumors. A select group of patients can achieve long-term survival after resection.

KEYWORDS:

Lung; Metastasectomy; Metastases; Prognostic factors; Resection

PMID:
19578657
[PubMed - indexed for MEDLINE]
PMCID:
PMC2705143
Free PMC Article
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