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J Cardiovasc Comput Tomogr. 2009 Jul-Aug;3(4):212-23. doi: 10.1016/j.jcct.2009.06.001. Epub 2009 Jun 6.

Outcomes research in cardiovascular imaging: report of a workshop sponsored by the National Heart, Lung, and Blood Institute.

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  • 1Division of Cardiovascular Medicine, Duke University Medical Center, 7022 North Pavilion DUMC, PO Box 17969, Durham, North Carolina 27715, USA. pamela.douglas@duke.edu

Abstract

In July of 2008, the National Heart, Lung, and Blood Institute convened experts in noninvasive cardiovascular imaging, outcomes research, statistics, and clinical trials to develop recommendations for future randomized controlled trials of the use of imaging in: 1) screening the asymptomatic patient for coronary artery disease; 2) assessment of patients with stable angina; 3) identification of acute coronary syndromes in the emergency room; and 4) assessment of heart failure patients with chronic coronary artery disease with reduced left ventricular ejection fraction. This study highlights several possible trial designs for each clinical situation.

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