Cancer Cell. 2009 Jul 7;16(1):7-8.

Pancreatic cancer--could it be that simple? A different context of vulnerability.

Source

Translational Genomics Research Institute, Phoenix, AZ 85004, USA. dvh@tgen.org

Abstract

In a recent issue of Science, Olive and colleagues document that inhibition of Hedgehog (Hh) signaling in a genetically engineered mouse model of pancreatic cancer can enhance the intratumor concentration of certain anticancer drugs. Could this finding provide us with a new method to attack pancreatic cancer?

PMID:: 19573807; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

Hedgehog Proteins

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Medical

Pancreatic Cancer - MedlinePlus Health Information

Miscellaneous

Mouse Genome Informatics (MGI)

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