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Chem Commun (Camb). 2009 Jul 21;(27):4040-2. doi: 10.1039/b904055b. Epub 2009 Jun 10.

Cell-based in vivo dual imaging probes using genetically expressed tags and chemical contrast agents.

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  • 1Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Kohoku-ku, Yokohama, 223-8522, Japan.


We report a method for specifically labelling the surface of cells with two kinds of chemical probes (near-infrared (NIR) fluorescent probes and magnetic resonance (MR) imaging probes) via two genetically expressed tags, and demonstrate the application for in vitro and in vivo dual imaging.

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