Features of contemporary theories of rape are integrated with information on neurohormonal variables to formulate a synthesized theory of rape. It consists of four propositions: (a) Rape is motivated by two largely unlearned drives (a sex drive and a drive to possess and control). (b) Natural selection has favored men who more readily learn forced copulatory tactics than women and women who are more inclined than men to resist forced copulations. (c) The tendency to use forced copulatory tactics is largely a function of the strength of an individual's sex drive plus estimates of the probability of success minus the probability of being punished, divided by sensitivity to aversive stimuli. (d) Genes that have evolved primarily on the Y chromosome affect neurohormonal functioning in ways that alter the strength of the sex drive and sensitivity to aversive stimuli and thereby affect individual probabilities of committing rape.