Format

Send to:

Choose Destination
See comment in PubMed Commons below
Insect Biochem Mol Biol. 2009 Apr;39(4):245-53. doi: 10.1016/j.ibmb.2009.01.008. Epub 2009 Feb 7.

The molecular mechanisms of cuticular melanization: the ecdysone cascade leading to dopa decarboxylase expression in Manduca sexta.

Author information

  • 1Faculty of Agriculture and Life Sciences, Hirosaki University, Hirosaki, Japan. hiruma@cc.hirosaki-u.ac.jp

Abstract

Many insect developmental color changes are known to be regulated by both ecdysone and juvenile hormone. Yet the molecular mechanisms underlying this regulation have not been well understood. This review highlights the hormonal mechanisms involved in the regulation of two key enzymes [dopa decarboxylase (DDC) and phenoloxidase] necessary for insect cuticular melanization, and the molecular action of 20-hydroxyecdysone on various transcription factors leading to DDC expression at the end of a larval molt in Manduca sexta. In addition, the ecdysone cascade found in M. sexta is compared with that of other organisms.

PMID:
19552890
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk