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Lab Anim (NY). 2009 Jul;38(7):246-7. doi: 10.1038/laban0709-246.

A simple method for assessing analgesic requirements and efficacy in rodents.

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  • 1Covance Inc., Greenfield, IN, USA.

Abstract

Evaluation of pain in the clinical setting is an ongoing challenge for veterinarians, researchers and IACUCs. Behavioral assessment, a common technique for evaluating pain, is subjective and difficult to translate into quantifiable data. The authors propose measuring changes in body weight, food consumption and water consumption as a simple and objective method for evaluating postsurgical pain and analgesic efficacy in rodents.

PMID:
19543263
[PubMed - indexed for MEDLINE]
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