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Hum Vaccin. 2009 Aug;5(8):520-8. Epub 2009 Aug 13.

Advances in dengue vaccine development.

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  • 1Naval Medical Research Center, Silver Spring, MD, USA. Kanakatte.raviprakas@med.navy.mil


Dengue viruses are the most important arboviruses causing human disease. Expansion of the disease in recent decades to include more geographical areas of the world, an appreciation of the disease burden and market potentials have spurred a flurry of activity in the development of vaccines to combat dengue viruses. Recent progress in this area and some of the obstacles associated with this development are discussed.

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