Vaccine. 2009 Aug 21;27 Suppl 3:C19-21. Epub 2009 Jun 16.

Understanding the link between pneumococcal serotypes and invasive disease.

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Instituto de Atención Pediátrica, Universidad de Ciencias Médicas, P.O. Box 607-1150, San Jose, Costa Rica.

Abstract

To determine the relationship between serotypes and the burden of pneumococcal disease in Latin American children, population- and laboratory-based surveillance data for the region were evaluated. Streptococcus pneumoniae continues to be an important bacterial pathogen causing infections in children. A seven-valent pneumococcal conjugate vaccine (PCV7) has been documented to be extremely effective in the prevention of invasive and non-invasive S. pneumoniae infections due to vaccine serotypes. However, due to evolving epidemiology, there is a need to enhance S. pneumoniae serotype coverage in future generation vaccines, complemented by ongoing surveillance of pneumococcal serotypes following vaccine introduction.

PMID:: 19535183; [PubMed - indexed for MEDLINE]

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Research Support, Non-U.S. Gov't

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Pneumococcal Infections - MedlinePlus Health Information

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