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Antigenic shift of visna virus in persistently infected sheep.
Visna viruses isolated from persistently infected sheep were antigenically distinct from the plaque-purified virus used for inoculation. The selection of antigenic variants under antibody pressure, thought to occur in vivo, was reproduced in sheep cell cultures inoculated with plaque-purified visna virus and maintained in antibody. Antigenic shift may be a mechanism for persistence of virus in slow or recurrent viral infections.
PMID: 195339 [PubMed - indexed for MEDLINE]
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Cited by 50 PubMed Central articles
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Rapid evolution of the neutralizing antibody response to HIV type 1 infection.
Richman DD, Wrin T, Little SJ, Petropoulos CJ.
Proc Natl Acad Sci U S A. 2003 Apr 1; 100(7):4144-9. Epub 2003 Mar 18.
[Proc Natl Acad Sci U S A. 2003]
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Naturally occurring mutations within 39 amino acids in the envelope glycoprotein of maedi-visna virus alter the neutralization phenotype.
Skraban R, Matthíasdóttir S, Torsteinsdóttir S, Agnarsdóttir G, Gudmundsson B, Georgsson G, Meloen RH, Andrésson OS, Staskus KA, Thormar H, et al.
J Virol. 1999 Oct; 73(10):8064-72.
[J Virol. 1999]
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Use of a recombinant maedi-visna virus protein ELISA for the serologic diagnosis of lentivirus infections in small ruminants.
Pasick J.
Can J Vet Res. 1998 Oct; 62(4):307-10.
[Can J Vet Res. 1998]
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