A descriptive, qualitative study using Watson's theory of human care was conducted to explore the experiences of persons with adult polycystic kidney disease (APKD) and their at-risk family members. The analysis of the data identified four major themes: (a) knowledge about APKD, (b) attitudes toward APKD, (c) attitudes toward genetic testing, and (d) family planning decisions. Quotations that illustrate common subject responses are included in the discussion of each thematic unit.