Birth Defects Res C Embryo Today. 2009 Jun;87(2):182-91.

Gene regulatory networks in embryonic stem cells and brain development.

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Institute for Systems Biology, Seattle, Washington 98103, USA.

Abstract

Embryonic stem cells (ESCs) are endowed with the ability to generate multiple cell lineages and carry great therapeutic potentials in regenerative medicine. Future application of ESCs in human health and diseases will embark on the delineation of molecular mechanisms that define the biology of ESCs. Here, we discuss how the finite ESC components mediate the intriguing task of brain development and exhibit biomedical potentials to cure diverse neurological disorders.

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Gene regulatory networks in embryonic stem cells and brain development.

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