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Opt Express. 2006 Sep 4;14(18):8138-53.

Spectroscopic phase-dispersion optical coherence tomography measurements of scattering phantoms.

Abstract

We demonstrate a novel technique to determine the size of Mie scatterers with high sensitivity. Our technique is based on spectral domain optical coherence tomography measurements of the dispersion that is induced by the scattering process. We use both Mie scattering predictions and dispersion measurements of phantoms to show that the scattering dispersion is very sensitive to small changes in the size and/or refractive index of the scatterer. We also show the light scattered from a single sphere is, in some cases, non-minimum phase, and therefore the phase of the scattered light is independent of the intensity. Phase dispersion measurements may have application to distinguishing the size and refractive index of scattering particles in biological tissue samples.

PMID:
19529186
[PubMed]
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